Tylenol PM Extra Strength Nighttime Pain Reliever and Sleep Aid Caplets help relieve minor aches and pains and help you fall asleep fast for a more restful sleep. This nighttime pain relief medicine provides 500 mg of acetaminophen and 25 mg of diphenhydramine hydrochloride in each caplet. Both a pain reliever and non-habit forming sleep aid, it is formulated to help you fall asleep and stay asleep while also relieving headaches and minor aches and pain.